104-1 |
|
S. MERTENS-TALCOTT, Dept. of Pharmaceutics, Univ. of Florida, 1600 SW Archer Road, JHMHC, POB 100494, Gainesville, FL 32610-0494 The use of drugs in the treatment of chronic diseases such as coronary heart disease as well as the application of alternative medicine, including the consumption of phytochemical-rich foods and dietary supplements, has been increasing in the United States within the last decade. It has been shown that certain drugs may interact with phytochemicals from foods or dietary supplements, which may lead to alterations in the absorption, metabolism, and excretion of drugs. The discovery of drug interactions with grapefruit juice, may present a major challenge for fruit- and vegetable-processing industry, including manufacturers of juices and beverages, dietary supplements, and specifically the grapefruit-processing industry.This introduction will give a general overview of the history of food-drug interactions and the most recent developments in the research area. Moreover, the biochemical principles of currently known mechanisms of interaction will be explained.
Session 104, Food-drug interactions: A new challenge for phytochemical research and industry
2005 IFT Annual Meeting, July 15-20 - New Orleans, Louisiana |