114E-12 |
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K.-Y. PARK1, J.-Y. Yoon1, S.-M. Choi1, K.-O. Jung1, S.-H. Kim2, I.-S. Ahn1, and M.-S. Do3. (1) Dept. of Food Science and Nutrition, Pusan National University, 30 Jangjun-dong, Keumjung-gu, Busan, 609-735, South Korea, (2) School of Food Science, Dongju College, Goejeong 3-dong, Saha-gu, Busan, 609-735, South Korea, (3) Dept. of Life and Food Science, Handong University, Heunhae-eup, Buk-gu, Pohang, 791-708, South Korea Kimchi is a traditional fermented vegetable food. Kimchi is made with baechu and sub-ingredients such as red pepper powder (RPP), radish, garlic, ginger, green onion, etc. RPP and kimchi intake in the rats reversed the effects of high fat diet on weight gain and blood and tissue lipids, and that kimchi did so more effectively than RPP alone. To elucidate mechanisms of antiobestic activity of kimchi, effects of kimchi ingredients on body weight, the levels of triglyceride and cholesterol in rats and leptin and glycerol levels in adipocytes were evaluated. SD rats were raised for four weeks with normal diet (AIN-93M diet), high fat diet (HFD), and diets containing 10% kimchi (50% RPP by dry weight) and 5% kimchi ingredients in the HFD. Body, organ, and fat pad weights; and total lipid, triglyceride and cholesterol concentrations in blood and tissues were evaluated. Leptin and glycerol levels were also determined in mature adipocytes. Garlic, ginger, green onion, and radish added HFD significantly reduced weight gain compared to the beachu and RPP added HFD and HFD (p<0.05). Kimchi ingredients significantly decreased the weight of epididymal and perirenal fat pad. Especially, garlic and raddish added diet groups exhibited the lowest weight gain (p<0.05) and significantly reduced the content of triglyceride and cholesterol in the fat tissues that increased by HFD. Garlic and raddish added diets were also effective in lowering serum triglyceride and cholesterol level. Treatment of mature fat cells with garlic, ginger and green onion decreased leptin secretion. Radish, garlic and green onion increased glycerol secretion. These results suggested that garlic and radish showed the most effective on reducing body fat gain and lipid values of adipose tissues and serum and increasing lipolysis of mature adipocytes among the kimchi ingredients.
Session 114E, Nutraceuticals & Functional Foods: Bioactivity measurement and mechanism
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