33G-23 |
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F. G. LOARCA-PIÑA1, E. Rodríguez-Muñoz2, L. Manzo-Bonilla1, G. Herrera-Ruíz3, E. Mercado-Silva4, G. Pedraza-Aboytes2, and R. Camacho-Reynoso4. (1) Programa de Posgrado en Alimentos del Centro de la República, Universidad Autónoma de Querétaro. Facultad de Química, Centro Universitario, Cerro de las Campanas S/N, Querétaro, 76010, Mexico, (2) Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario, Cerro de las Campanas S/N, Querétaro, 76010, Mexico, (3) Facultad de Ingeniería, Universidad Autónoma de Querétaro, Centro Universitario, Cerro de las Campanas S/N, Querétaro, 76010, Mexico, (4) Programa de Posgrado en Alimentos del Centro de la República, Universidad Autónoma de Querétaro, Centro Universitario S/N, Cerro de las Campanas, Querétaro, 76010, Mexico Chronic diseases such as cardiovascular, cancer and diabetes Mellitus, are the major causes of death in Mexico. Epidemiological studies have found a strong association between food sources of lycopene or plasma concentrations of lycopene and reduced risk for certain types of cancers, and also suggests a potential benefit in reducing cardiovascular disease risk. In tomatoes, lycopene makes up about 75 percent of the total carotenoids present. However, several factors influence the lycopene content of tomatoes and may vary considerably from region to region depending upon growing conditions. The objective was to obtain a lycopene oleoresin from tomato non commercial having the biological properties above mentioned, and propose its use in the industry. Total lycopene content from tomatoes (Lycopersicon esculentum) of Zedona and Gironda varieties at different stages of ripening, and growing in a greenhouse was quantified. The lycopene oleoresin obtained was screened for its antioxidant potential using the beta-carotene and 1,1-diphenyl-2-picrylhydrazyl (DPPH) in vitro models. The lycopene oleoresin exhibited antioxidant activity that correlated with lycopene content and inhibited DPPH significantly in a dose-dependent manner. In addition, lycopene oleoresin was significantly more effective than a lycopene standard. To examine the effect of lycopene oleoresin against aflatoxin B1 (AFB1) mutagenicity, the microsuspension assay with tester strain TA100 and TA98 of Salmonella typhymurium was used. The antimutagenic effect correlated with lycopene content and showed also a dose-dependent manner.
Session 33G, Nutraceuticals & Functional Foods: Lipid and probiotic functional foods
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