15E-3 |
Amaranth fiber: Effect in lipid levels of rat serum |
G. ALVAREZ-DÍAZ1, R. Mora-Escobedo1, G. Chamorro-Ceballos2, M. Salazar-Jacobo3, and L. Garduño-Siciliano2. (1) Departamento de Graduados en Alimentos, Escuela Nacional de Ciencias Biológicas, IPN, Carpio y Plan de Ayala, Col. Sto. Tomás, México, D.F., 11340, Mexico, (2) Laboratorio de Toxicología Preclínica, Escuela Nacional de Ciencias Biológicas, IPN, Carpio y Plan de Ayala, Col. Sto. Tomás, Mexico, 11340, Mexico, (3) Laboratorio de Toxicología Preclínica, Carpio y Plan de Ayala, Col. Sto. Tomás, Mexico, 11340, Mexico The objective of this study was to determine if the flour of germinated amaranth (0, 24 and 36 h) reduces serum cholesterol, due to its soluble dietary fiber content, in rats. The influence of the consume of germinated Amaranthus hypochondriacus on serum lipids, of male Wistar rats feeding simultaneously with hypercholesterolemic diet, during 21 days was determined. The diets were adjusted to obtain 10% of total dietary fiber (3.6% dietetic soluble fiber), and the necessary conditions to carry out hypercholesterolemic conditions. In order to compare the effect of germinated amaranth flour on total cholesterol, triglycerides, low density lipoprotein cholesterol (LDL), and high density lipoprotein cholesterol (HDL) additional hypocholesterolemic diets as oat, cellulose and squalene were tested. Squalene is an amaranth compound that could be involved in cholesterol biosynthesis. The diets with germinated amaranth flour (24 and 36 h ) lowed total cholesterol (83.3 + 11.2 and 93.4 + 9.1 mg/dL) to the same levels of squalene diets (85.6 + 8.5 mg/dL); but more efficiently than cellulose (135 + 12.6 mg/dL) (p< 0.05). The lower values of LDL obtained by germinated amaranth flours (95.6 + 13.7 and 112.0 + 11.5 mg/dL) were similar to those obtained with oats (93.7 + 10.3 mg/dL), squalene (95.6 + 9.8 mg/dL) and normal diet (95.4 + 7.5 mg/dL); but lower that cellulose (154.0 + 14.0 mg/dL) (p< 0.05). All study groups, with exception of squalene, showed higher values of HDL than hypercholesterolemic group (p< 0.05). However the highest values corresponded to germinated amaranth flour and oat diets. There was not difference on the rats weigh when they were compared with hypercholesterolemic group. Both amaranth diets increased feces rat weight. Toxicity problems were not found when the rats were fed germinated amaranth flour, because changes in relative liver weight could not be found.
Session 15E, Nutraceuticals & Functional Foods I
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