73D-3 |
Release control of antimicrobial agents from biodegradable film |
Y. S. PARK1, G. H. Shin2, D. S. Cha2, and H. J. Park2. (1) Depatment of Information, Korea Health Industry Development Institute, 5Ka Anam-Dong, Sungbuk-Ku, Seoul, 156-050, South Korea, (2) Graduate School of Biotechnology, Korea University, 5Ka Anam-Dong, Sungbuk-Ku, Seoul, 136-701, South Korea Since potassium sorbate and sodium benzoate have a wide range of bacteriostatic and mycostatic properties, the biodegradable films of methylcellulose/ hydroxypropylmethylcellulose (MC/HPMC), chitosan or K-carrageenan incorporated with potassium sorbate or sodium benzoate can be used effectively as a potential °°antimicrobial packaging°± materials. Our objectives were a) to produce biodegradable antimicrobial package films b) to measure the amount of antimicrobial agents release from the films by HPLC. The film forming solutions were added to the spreader of thin-layer chromatography (TLC) plates and plated onto 20°¿20 §¯ TLC glass plates at a thickness of 0.75mm. The agar well diffusion method was used to detect the antimicrobial activity against Penicillium notatum ATCC 11625 and Rhodotorula rubra CBS7014. The released amounts of sodium benzoate and potassium sorbate from the films were measured by HPLC. The mechanical properties of the films were measured by on instron and the structure of the films were observed by SEM. Release rates of antimicrobial agents in MC/HPMC based films were faster than K-carrageenan or chitosan based films. Release rates were faster at pH 4 than pH 7. At pH 4 approximately 15% of antimicrobial agents were released from the films in the first 10min from MC/HPMC based film, 30min from K-carrageenan or chitosan based film. The films prepared in this study showed a great potential for commercial application of antimicrobial package to control the shelf life of foodstuff.
Session 73D, Food Packaging
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